Nigerian foodstuffs with prostate cancer chemopreventive polyphenols

Plant Polyphenols as Chemopreventive Agents for Lung Cancer

Lung cancer may be prevented by a diet rich in fruits and vegetables as they are enriched with dietary antioxidant polyphenols, such as flavonoids, proanthocyanidins, lignans, stilbenes, and phenolic acids. Dietary polyphenols exert a wide range of beneficial biological functions beyond their antioxidative properties and are involved in regulation of cell survival pathways leading to anticarcin...

Cancer chemopreventive activity and bioavailability of tea and tea polyphenols.

Consumption of tea (Camellia sinensis) has been associated with many health benefits including the prevention of cancer. Based on in vitro experiments, many mechanisms have been proposed to account for the cancer chemopreventive activity. The importance of some of these mechanisms in vivo remains in question due to an incomplete understanding of the bioavailability of the polyphenolic compounds...

Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease.

PURPOSE We have shown previously that oral feeding of green tea polyphenols (GTP) to transgenic adenocarcinoma of the mouse prostate mice in a purely chemopreventive setting significantly inhibits prostate cancer development. To translate this to a human situation, the present study was designed to identify the stage of prostate cancer that is most vulnerable to chemopreventive intervention by ...

Utilizing Micronutrients as a Chemopreventive Strategy for Prostate Cancer

Chemopreventive Target for Prostate Cancer: Prostatic Intraepithelial Neoplasia

Prostate cancer is one of the most frequently diagnosed malignancies among the male population and the second common cancer-related death worldwide after lung cancer (Jemal et al., 2010). It is estimated that 30% of male older than 50 years are harboring microscopic transformation of adenocarcinoma within the prostate gland. Because of the dramatic rise in the incidence of prostate cancer with ...